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Cochrane Central Register of Controlled Trials (Cochrane Library, Issue 2, 2005), Medline (1966 to April 2005), EMBASE/Excerpta Medica (1980–2005), CINAHL (1982–2005), BIOSIS, AMED, bibliographies of relevant articles, pharmaceutical companies, content experts, and registries of ongoing trials (eg, Meta Register of Controlled Trials and US National Institute of Health register).
Study selection and assessment:
randomised controlled trials (RCTs), crossover trials, and quasi-randomised trials that compared any type of laxative with placebo or no therapy in patients …
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