Oestrogen plus progestogen v placebo in postmenopausal women*

Annualised percentage developing coronary heart disease (CHD)
Outcomes at mean 5.3 yearsOestrogen plus progestogenPlaceboAdjusted hazard ratio (95% CI)
*CI defined in glossary. Hazard ratio adjusted for the presence or absence of previous coronary revascularization and sequential monitoring.
†Not significant.
All CHD0.39%0.33%1.24 (0.97 to 1.60)†
Non-fatal myocardial infarction (MI)0.31%0.25%1.28 (0.96 to 1.70)†
Nonfatal MI (excluding silent MI)0.31%0.24%1.30 (0.97 to 1.74)†
Death caused by CHD0.08%0.08%1.10 (0.65 to 1.89)†