Primary prevention strategy v control (alternate intervention or nothing) for adolescents*

Weighted event rates
OutcomesNumber of trialsPrimary preventionControlPooled odds ratio (OR) (95% CI)†
*Abbreviations defined in glossary. Weighted event rates provided by author. Follow up ranged from 2–54 months. †For intercourse and pregnancy outcomes, OR <1.0 favours intervention; for contraception outcomes, OR >1 favours intervention. ‡Significant heterogeneity among trials. §Statistically significant.
Women
Delayed initiation of intercourse13 (n=9642)22%20%1.12 (0.96 to 1.30)
Used contraception at every intercourse8 (n=1967)45%44%0.95 (0.69 to 1.30)
Used contraception at last intercourse5 (n=799)50%46%1.05 (0.50 to 2.19)‡
Pregnancy12 (n=8019)4.4%4.8%1.04 (0.78 to 1.40)
Men
Delayed initiation of intercourse11 (n=7418)29%30%0.99 (0.84 to 1.16)
Used contraception at every intercourse3 (n=1505)36%38%0.90 (0.70 to 1.16)
Used contraception at last intercourse4 (n=1262)69%64%1.25 (0.99 to 1.59)
Pregnancy in partners5 (n=3759)3.4%2.4%1.54 (1.03 to 2.29)§