Mean differences in peak expiratory flow (PEF) and forced expiratory volume in one second (FEV1) between treatment with salmeterol v an increased dose of inhaled steroids in symptomatic asthma (in favour of added salmeterol) (all p<0.001 except * p<0.01)
| Outcomes | 3 months | 6 months |
|---|---|---|
| PEF (litre/min) | 22.4 (15 to 30) | 27.7 (19 to 36) |
| FEV1 (litre) | 0.10 (0.04 to 0.16) | 0.08 (0.02 to 0.14)* |