Table 4

Summary of an economic analysis on central line catheters and catheter related blood stream infection (CRBSI)

FeatureStudy by Veenstra et al, 1999
Overall study designCost effectiveness analysis using a decision analytic model
Perspective of analysisHealthcare payer
Alternatives comparedStandard or antiseptic impregnated multilumen central venous catheters
Effect measuresIncidence of CRBSI, death
Source of effectiveness dataRandomised controlled trials, meta-analysis, case control studies
Source of quality of life (utility) weightsN/A
Estimates of resource useUniversity of Washington Medical Center and the literature
Source of cost dataDirect medical costs – University of Washington Medical Center and the literature
DiscountingN/A
Addressing uncertaintyMultivariate sensitivity analyses with varying estimates of direct medical costs, incidence of CRBSI, and death attributable to CRBSI or hypersensitivity reactionUnivariate sensitivity analyses for incremental costs: cost of CRBSI, relative risk of CRBSI, incidence of CRBSI, and additional catheter cost Univariate sensitivity analyses for incremental incidence of death: relative risk of CRBSI, incidence of CRBSI, probability of death attributable to CRBSI, and probability of hypersensitivity