1. | Is the appropriate economic evaluation method used? |

2. | Are the alternative courses of action appropriate and well defined? |

3. | Is the perspective of the analysis stated, and are appropriate costs considered? |

4. | If cost utility analysis methods are used, are the utilities (patient preferences) reasonable? |

5. | Are the events used comprehensive, and are the probabilities of events derived from credible sources? |

6. | Are data on costs and outcomes appropriately discounted? |

7. | Is uncertainty in the data adequately addressed? |