Oestrogen plus progestogen (Oest + Prog) v placebo for postmenopausal women*

Outcomes at mean 5.6 yearsOest + ProgPlaceboHazard ratio (95% CI)
*CI defined in glossary.
†Not significant.
Cases of breast cancer (all)2451851.24 (1.02 to 1.50)
Cases of invasive breast cancer1991501.24 (1.01 to 1.54)
Cases of in situ breast cancer47371.18 (0.77 to 1.82)†