A 30 mg/kg loading dose of acetaminophen v a 15 mg/kg maintenance dose in febrile children*
| Outcomes | 30 mg/kg | 15 mg/kg | Mean difference (95% CI) |
|---|---|---|---|
| Time to obtain temperature < 38.5°C (min) | 110.7 | 139.5 | −28.8 (−66.5 to −8.9) |
| Maximum temperature decrease (°C) | 2.3 | 1.8 | 0.5 (0.3 to 0.8) |
| Duration of rectal temperature < 38.5°C (min) | 255.2 | 200.8 | 54.4 (14.7 to 94.2) |
| Outcome at 6 hours | 30 mg/kg | 15 mg/kg | RRR (CI) | NNT (CI) |
|---|---|---|---|---|
| *Abbreviations defined in glossary; RRR, NNT and CI calculated from data in article. | ||||
| Received a temperature altering treatment | 10% | 26% | 61% (10 to 83) | 7 (4 to 52) |