Simvastatin v placebo in patients at high risk of vascular disease*

Outcomes at 5 yearsSimvastatinPlaceboRRR (95% CI)NNT (CI)
*Abbreviations defined in glossary; NNT and CI calculated from control event rate and rate ratio reported in article.
†Non-fatal myocardial infarction or coronary death, stroke, or revascularisation procedure.
≥1 major vascular event†20%25%24% (19 to 28)17 (15 to 21)
≥1 stroke4.3%5.7%25% (15 to 34)71 (52 to 117)
≥1 ischaemic stroke2.8%4.0%30% (19 to 40)84 (63 to 133)