TY - JOUR T1 - Limited evidence that single-dose oral ibuprofen plus codeine is more effective for postoperative pain than either drug alone JF - Evidence Based Nursing JO - Evid Based Nurs DO - 10.1136/eb-2013-101421 SP - ebnurs-2013-101421 AU - Jaime L Baratta AU - Kishor Gandhi AU - Eugene R Viscusi Y1 - 2013/07/29 UR - http://ebn.bmj.com/content/early/2013/07/29/eb-2013-101421.abstract N2 - Commentary on: Derry S, Karlin SM, Moore RA. Single dose oral ibuprofen plus codeine for acute postoperative pain in adults. Cochrane Database Syst Rev 2013;3:CD010107.OpenUrlPubMed Professional societies (American Society of Anesthesiology (ASA) and the European Society of Anaesthesiology (ESA)) recommend maximising non-opioid over opioid analgesics and utilising a multimodal approach to perioperative pain management. This systematic review (SR) examines the effects of combining codeine and ibuprofen. The authors of SR conclude that ibuprofen and codeine combinations may provide enhanced efficacy. Future research should focus on whether combination agents provide better analgesia than their individual constituent alone. Postoperative pain control remains challenging. Historically, there has been a reliance on opioids for pain management. The American Society of Anesthesiology's (ASA's) most recent guidelines recommend maximising non-opioid agents with around-the-clock dosing and using opioids supplementally.1 Derry and colleagues performed a meticulous SR examining the analgesic efficacy of single-dose ibuprofen and codeine … ER -