TY - JOUR T1 - Cognitive behavioural therapy improved psychiatric symptoms in drug refractory schizophrenia JF - Evidence Based Nursing JO - Evid Based Nurs SP - 116 LP - 116 DO - 10.1136/ebn.3.4.116 VL - 3 IS - 4 A2 - , Y1 - 2000/10/01 UR - http://ebn.bmj.com/content/3/4/116.abstract N2 - Sensky T, Turkington D, Kingdon D, et al.A randomized controlled trial of cognitive-behavioral therapy for persistent symptoms in schizophrenia resistant to medication.Arch Gen Psychiatry2000 Feb;57:165–72OpenUrlCrossRefPubMedWeb of Science QUESTION: Is cognitive behavioural therapy (CBT) more effective than a befriending intervention for reducing psychiatric symptoms in drug refractory schizophrenia? Randomised (allocation concealed), blinded (outcome assessors), controlled trial with 9 months of follow up after treatment.5 clinical services in the UK (Newcastle, Cleveland, Durham, and 2 in west London).90 patients who were 16–60 years of age (mean age 39 y, 59% men, 89% white), met ICD-10 research and DSM-IV criteria for schizophrenia, and had symptoms causing distress or dysfunction for ≥6 months despite adequate doses of antipsychotic drugs. Follow up was 100% for all outcomes except for scores on the Scale for Assessment of Negative Symptoms (SANS), which had 98% follow up.Patients were allocated to CBT (n=46) or befriending (n=44). … ER -