TY - JOUR T1 - Topical chloramphenicol was not effective for acute infective conjunctivitis in children JF - Evidence Based Nursing JO - Evid Based Nurs SP - 12 LP - 12 DO - 10.1136/ebn.9.1.12 VL - 9 IS - 1 A2 - , Y1 - 2006/01/01 UR - http://ebn.bmj.com/content/9/1/12.abstract N2 - Rose PW, Harnden A, Brueggemann AB, et al. Chloramphenicol treatment for acute infective conjunctivitis in children in primary care: a randomised double-blind placebo-controlled trial. Lancet 2005;366:37–43.OpenUrlCrossRefPubMedWeb of Science Q In children with acute infective conjunctivitis, is topical chloramphenicol effective for inducing clinical cure?Design:randomised controlled trial.Allocation:concealed.Blinding:blinded (patients, healthcare providers, data collectors, outcome assessors, and data analysts).Follow up period:7 days for the primary outcome plus an extra 5 weeks to assess relapse.Setting:12 primary practices in Oxfordshire, UK.Patients:326 children 6 months to 12 years of age (mean age 3 y, 53% boys) who had acute infective conjunctivitis. Exclusion criteria included allergy to chloramphenicol, use of antibiotics (current or within the previous 48 h), evidence of severe infection, and children … ER -