TY - JOUR T1 - Protocol directed sedation by nurses reduced the duration of mechanical ventilation in critically ill patients JF - Evidence Based Nursing JO - Evid Based Nurs SP - 82 LP - 82 DO - 10.1136/ebn.3.3.82 VL - 3 IS - 3 A2 - , Y1 - 2000/07/01 UR - http://ebn.bmj.com/content/3/3/82.abstract N2 - Brook AD, Ahrens TS, Schaiff R, et al.Effect of a nursing-implemented sedation protocol on the duration of mechanical ventilation.Crit Care Med1999 Dec;27:2609–15OpenUrlCrossRefPubMedWeb of Science QUESTION: Is protocol directed sedation by nurses associated with a shorter duration of mechanical ventilation than traditional, non-protocol directed sedation in critically ill patients with acute respiratory failure? Randomised (allocation concealed), unblinded, controlled trial.A medical intensive care unit (ICU) in a university teaching hospital in St Louis, Missouri, USA.321 patients >17 years of age (mean age 58 y, 51% women, 58% white) who required mechanical ventilation for acute respiratory failure. Patients were excluded if they were temporarily admitted to the medical ICU and awaiting admission to a surgical ICU.At the time of mechanical ventilation, patients were allocated to 1 of 2 groups. 162 patients received protocol directed sedation by nurses, in which … ER -