TY - JOUR T1 - Postoperative ibuprofen increased bleeding complications in hospital and did not improve pain or physical function at 6–12 months after total hip replacement JF - Evidence Based Nursing JO - Evid Based Nurs SP - 57 LP - 57 DO - 10.1136/ebn.10.2.57 VL - 10 IS - 2 A2 - , Y1 - 2007/04/01 UR - http://ebn.bmj.com/content/10/2/57.abstract N2 - Fransen M, Anderson C, Douglas J, et al for the HIPAID Collaborative Group. Safety and efficacy of routine postoperative ibuprofen for pain and disability related to ectopic bone formation after hip replacement surgery (HIPAID): randomised controlled trial. BMJ 2006;333:519.OpenUrlAbstract/FREE Full Text Q In patients having total hip replacement surgery, does 14 days of postoperative ibuprofen (as prophylaxis for ectopic bone formation) reduce pain and improve physical function 6–12 months after surgery? What are the effects on bleeding complications?Design:randomised, placebo controlled trial (HIPAID).Allocation:concealed.Blinding:blinded {patients, healthcare providers, data collectors, outcome assessors, data analysts, and monitoring committee}.* Follow up period:6–12 months after surgery {median 7.8 mo}.*Setting:20 hospitals in Australia and New Zealand.Patients:902 patients (mean age 66 y, 54% men) who were identified within 24 … ER -