TY - JOUR T1 - Review: children <2 years of age with bilateral acute otitis media and children with otorrhoea benefit most from antibiotics JF - Evidence Based Nursing JO - Evid Based Nurs SP - 45 LP - 45 DO - 10.1136/ebn.10.2.45 VL - 10 IS - 2 A2 - , Y1 - 2007/04/01 UR - http://ebn.bmj.com/content/10/2/45.abstract N2 - Rovers MM, Glasziou P, Appelman CL, et al. Antibiotics for acute otitis media: a meta-analysis with individual patient data. Lancet 2006;368:1429–35.OpenUrlCrossRefPubMedWeb of Science Q Which subgroups of children with acute otitis media benefit from treatment with antibiotics?Data sources:Cochrane Library, PubMed, EMBASE/Excerpta Medica, and proceedings of international symposia.Study selection and assessment:randomised controlled trials (RCTs) that compared antibiotics with placebo or no treatment in children 0–12 years of age with acute otitis media and assessed pain and fever. 6 RCTs (n = 1643, mean age 3.4 y [range 0–11], 50% boys) met the selection criteria, and the authors were willing to supply raw data. Quality assessment based on 4 criteria (randomisation procedure; allocation concealment; follow up; and blinding of patients, caregivers, and outcome assessors) showed … ER -