TY - JOUR T1 - Environmental and dietary interventions in the first 5 years of life did not reduce the risk of asthma and allergic disease JF - Evidence Based Nursing JO - Evid Based Nurs SP - 44 LP - 44 DO - 10.1136/ebn.10.2.44 VL - 10 IS - 2 A2 - , Y1 - 2007/04/01 UR - http://ebn.bmj.com/content/10/2/44.abstract N2 - Marks GB, Mihrshahi S, Kemp AS, et al. Prevention of asthma during the first 5 years of life: a randomized controlled trial. J Allergy Clin Immunol 2006;118:53–61.OpenUrlCrossRefPubMedWeb of Science Q Does reduction in exposure to house dust mite (HDM) allergens and modification of dietary fatty acids in the first 5 years of life reduce the risk of asthma at 5 years of age?Design:randomised, 2×2 factorial, placebo controlled trial.Allocation:{concealed}.* Blinding:blinded {participants [diet intervention only] and outcome assessors}.*Follow up period:5 years.Setting:{recruitment in antenatal clinics of 6 hospitals in Sydney, Australia}.* Interventions were done in children’s homes.Participants:616 pregnant women (mean age 29 y), whose unborn singleton child was at increased risk of developing asthma because of asthma in a first degree relative. Infants born at <36 weeks’ gestation, with birth weight <2.5 kg or significant congenital malformation or … ER -