TY - JOUR T1 - <span hwp:id="article-title-1" class="article-title">Review: evidence on the effectiveness of interventions to improve patient adherence to prescribed medications is limited</span><span hwp:id="article-title-2" class="sub-article-title">Commentary</span> JF - Evidence Based Nursing JO - Evid Based Nurs SP - 109 LP - 109 DO - 10.1136/ebn.11.4.109 VL - 11 IS - 4 AU - Celia E Wills Y1 - 2008/10/01 UR - http://ebn.bmj.com/content/11/4/109.abstract N2 - R B HaynesProfessor R B Haynes, McMaster University, Hamilton, Ontario, Canada; bhaynes@mcmaster.caAre interventions to improve patient adherence to self- administered prescribed medications effective?Studies selected evaluated interventions to improve adherence to medications prescribed for medical disorders (including mental but not addiction disorders), had ⩾80% follow-up in each study group, reported both medication adherence and treatment outcomes, and had ⩾6 month follow-up in trials of long-term treatments that had positive initial results.Medline, CINAHL, EMBASE/Excerpta Medica, Cochrane Library, International Pharmaceutical Abstracts, PsycINFO, and Sociological Abstracts (all to Jan 2007); and reference lists were searched for randomised controlled trials (RCTs). Authors of relevant trials and reviews were contacted. 78 RCTs ({93}* unconfounded interventions, 10 with short-term treatment and {83}* with long-term treatment; n = 32–1113) met the selection criteria; 20 reported concealment of allocation. Conditions studied included asthma or chronic … ER -