TY - JOUR T1 - A low dose of albuterol (salbutamol) by metered dose inhaler (MDI) with a spacer was as effective as higher doses by MDI or low doses by nebuliser in children with mild acute asthma JF - Evidence Based Nursing JO - Evid Based Nurs SP - 12 LP - 12 DO - 10.1136/ebn.3.1.12 VL - 3 IS - 1 A2 - , Y1 - 2000/01/01 UR - http://ebn.bmj.com/content/3/1/12.abstract N2 - Schuh S, Johnson DW, Stephens D, et al.Comparison of albuterol delivered by a metered dose inhaler with spacer versus a nebulizer in children with mild acute asthma.J Pediatr1999 Jul;135:22–7OpenUrlCrossRefPubMedWeb of Science QUESTION: In children with mild acute asthma, is albuterol (salbutamol) delivered by a metered dose inhaler (MDI) with a spacer (standard low dose or higher, weight adjusted dose) as effective as albuterol delivered by a nebuliser? Randomised (concealed), blinded (patient and outcome assessor), controlled trial.A hospital emergency department in Toronto, Ontario, Canada.90 children who were 5–17 years of age (mean 9.2 y, mean baseline forced expiratory volume in 1 second [FEV1] 62.8%) who presented with acute asthma exacerbation between 0800 and 2200, could reliably perform pulmonary function testing, and had a baseline FEV1 of 50%–79% of the predicted value. Children were excluded if this was their first wheezing episode, they had used albuterol within 4 hours of the visit, had concurrent cardiopulmonary disease, or … ER -