eLetters

21 e-Letters

published between 2014 and 2017

  • Editors' Reply to eLetter from JC Platt
    EBM Editors

    Dear Mr Platt

    Many thanks for your eLetter regarding an abstract appearing in both EBM[1] and EBN[2] with different commentaries. In answer to your queries:
    First, when we have the same abstract appearing in both journals we do sometimes use the same commentary as well, however, if we think it doesn't fit our target audience we can require a fresh commentary. The risk is that, like all opinion, diff...

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  • Link to blinding Research Made Simple from July 2013
    Alison Twycross

    If you enjoyed this paper and want to know more about blinding read the EBN Research Made Simple paper Blinding: an essential component in decreasing risk of bias in experimental designs available from: Click here

    Conflict of Interest:

    None declared

  • Response to: A home-based, nurse-delivered exercise programme
    John C Platt

    Dear Editors

    The study:
    A home-based, nurse-delivered exercise programme reduced falls and serious injuries in people ³ 80 years of age. Robertson et al. Effectiveness and economic evaluation of a nurse delivered home exercise programme to prevent falls. 1: randomised controlled trial. [1]
    appeared in both Evidence-Based Medicine [2] and in Evidence-Based Nursing.[3]...

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  • Carlos K B Ferrari
    Dear Editor

    It is well documented that Free radicals (FRs) and their Oxidative Reactions are implicated in more than 70 diseases and disorders [1,2], including inflammatory reactions, such as alergies and rheumatoid arthritis. As FRs and Oxidative stress are also implicated in many cell death processes [3], many scientific activities are being done to discover possible protective effects of the antioxidant therapy [1]. Today...

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  • Author's Reply
    Andrew Jull

    Dear Editor

    Dr Parienti and colleagues have raised concerns [1] about a section of the commentary for which I am responsible. Their letter highlights the lack of a standard typology for trial design in clinical epidemiology. At the heart of this issue is not only what to call the different types of clinical trial, but how to analyse the results of each trial. Was the trial by Dr Parienti and colleagues a cluster randomi...

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  • Only cluster design lead to cluster effect
    Jean-Jacques Parienti

    Dear Editor

    On behalf our Study group, I would like to thank EBN’s Editors for their interest in our work.

    In their review, major concerns regarding the design and analysis of our study were raised by Drs Moralejo and Jull, mainly because antiseptic protocols were randomised by services (called "clusters") but outcome was analysed by patients. The authors concluded that while our trial is intriguing, "whether...

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  • Nicky Callum
    We would like to thank Carlos Kusano Bucalen Ferrari for taking the time to respond to the Commentary by Violeta Ribeiro (EBN 2002; 5:57). Mr Ferrari gives us an interesting overview of the biochemical effects of several antioxidants in laboratory studies. These kinds of studies are frequently the starting point for developing new drugs and treatments but it is important to emphasise that the results of in vitro studies in labo...
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  • Link to Research Made Simple, on what is a systematic review?
    Alison Twycross

    If you would like to know more about systematic reviews why not read the EBN Research Made Simple paper What is a systematic review? Available from: Click here

    Conflict of Interest:

    None declared

  • Link to Research Made Simple
    Alison Twycross

    If you enjoyed this EBN Notebook you may also like to read the EBN Research Made Simple paper looking at Qualitative data analysis: a practical example. This is available at: Click here

    Conflict of Interest:

    None declared

  • To learn more about "hypothesis testing and p values: how to interpret results and reach the right conclusion"
    Alison Twycross

    For more information about Hypothesis testing and p values: how to interpret results and reach the right conclusion see the EBN Research Made Simple paper published in April 2013.

    If you want to learn more about p values see EBN Research Made Simple paper "What is a p value and what does it mean?" from April 2012.

    These are both available at:

    Cli...

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