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Using meta-analysis: what exercise helps kids with excess weight the most?
  1. Marilyn Frenn
  1. College of Nursing, Marquette University, Milwaukee, Wisconsin, USA
  1. Correspondence to Dr Marilyn Frenn, College of Nursing, Marquette University, Milwaukee, Wisconsin, USA; marilyn.frenn{at}

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Commentary on: García-Hermoso A, López-Gil JF, Izquierdo M, et al. Exercise and insulin resistance markers in children and adolescents with excess weight: a systematic review and network meta-analysis. Jama Pediatrics. 2023;177(12):1276–84.

Implications for practice and research

  • Resistance exercises with aerobic training and high-intensity interval training reduced insulin resistance markers in 5–18 years old children with excess weight if done at least two to three times/week.

  • Low to moderate certainty of evidence in this meta-analysis1 requires further research to better determine the best approaches to reduce metabolic syndrome and diabetes.


The prevalence of childhood excess weight continues to grow, adding to risk of metabolic syndrome and type II diabetes.2 Rigorous search methods were used to examine types of physical activity effective in reducing the risks of excess weight. Following quality assessment, study results …

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  • Competing interests None declared.

  • Provenance and peer review Commissioned; internally peer reviewed.