Statistics from Altmetric.com
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.
Commentary on: Verhoeven JE, Han LKM, Lever-van Milligen BA, et al. Antidepressants or running therapy: comparing effects on mental and physical health in patients with depression and anxiety disorders. J Affect Disord 2023;329:19–29. doi: 10.1016/j.jad.2023.02.064.
Implications for practice and research
Supervised outdoor running at vigorous intensity leads to antidepressant and physical health benefits in outpatients with major depression or anxiety disorders.
More pragmatic exercise trials for mental health outpatients with heterogeneous symptomatology are needed.
Exercise is associated with antidepressant effects in clinical settings but relevant research in pragmatic (real-life) settings is scarce.1–3 Hence, Verhoeven et al4 in their pragmatic trial compared the mental and physical health benefits of running therapy versus antidepressant medication.
Participants were physically inactive adult outpatients with a current major depression or an anxiety disorder and were treated with benzodiazepines. Following a partial randomisation based on individual …
Competing interests None declared.
Provenance and peer review Commissioned; internally peer reviewed.