Article Text

Download PDFPDF
Risk of aspirin among pregnant women
  1. Hanumanthu R Jogu1,
  2. Pradeep Yarra2
  1. 1Wake Forest School of Medicine, Winston-Salem, North Carolina, USA
  2. 2Internal Medicine, University of Kentucky, Lexington, Kentucky, USA
  1. Correspondence to Pradeep Yarra, Internal Medicine, University of Kentucky, Lexington, Kentucky, USA; pya227{at}uky.edu

Statistics from Altmetric.com

Commentary on: Hastie R, Tong S, Wikström AK, et al. Aspirin use during pregnancy and the risk of bleeding complications: a Swedish population-based cohort study. Am J Obstet Gynecol. 2020 Jul 17:S0002-9378(20)30737-7. doi:10.1016/j.ajog.2020.07.023.

Implications for practice and research

  • Using aspirin for prevention of pre-eclampsia is associated with increased risk of postpartum haemorrhage, postpartum hematoma and possibly neonatal intracranial haemorrhage.

  • More liberal or universal administration of aspirin may have more risk than benefits due to bleeding risk, but still strongly advised in high-risk pre-eclampsia pregnant women.

  • Future prospective studies are needed to determine bleeding risks with widespread use of aspirin in pregnancy.

Context

Aspirin is widely offered to pregnant women at risk of developing pre-eclampsia, secondary to its anti-inflammatory and antiplatelet properties.1 There has been a trend towards increasing the use of aspirin universally to pregnant women, secondary to perceived safety of aspirin.2 Recent large randomised control trials report …

View Full Text

Footnotes

  • Competing interests None declared.

  • Provenance and peer review Commissioned; internally peer reviewed.

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.