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Association between COVID-19 and Kawasaki-like disease in children is a topic that needs further investigation
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  1. Saivash Moradi1,
  2. Mohammad Radgoodarzi2
  1. 1Medical Education Development Centre, Mazandaran University of Medical Sciences Faculty of Medicine, Sari, Iran
  2. 2Hazrat Rasoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran
  1. Correspondence to Professor Saivash Moradi, Mazandaran University of Medical Sciences Faculty of Medicine, Sari, Iran (the Islamic Republic of); d.smor86{at}yahoo.com

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Commentary on: Verdoni L, Mazza A, Gervasoni A, et al. An outbreak of severe Kawasaki-like disease at the Italian epicentre of the SARS-CoV-2 epidemic: an observational cohort study. Lancet 2020; 395: 1771–78. doi: 10.1016/S0140-6736(20)31103-X.

Implications for practice and research

  • Recent reports of incremental trends of Kawasaki (KD) disease among children in COVID-19 epidemic areas is a significant issue that cannot be simply ignored.

  • KD has a strict diagnostic criterion, so the attribution of a set of inflammatory symptoms in children with COVID-19 to KD requires more careful interpretation.

Context

The cause of Kawasaki disease (KD) as an acute febrile illness of childhood is not fully understood. Although certain epidemiologic and clinical features support an infectious origin, no single infectious aetiologic agent has been successfully identified.1 KD has a wide range of clinical and laboratory features, so can be …

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