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- general medicine (see internal medicine)
- protocols & guidelines
- infectious diseases
- intensive & critical care
Commentary on: Baghdadi JD, Wong MD, Uslan DZ et al. Adherence to the SEP-1 Sepsis Bundle in Hospital-Onset v. Community-Onset Sepsis: a Multicenter Retrospective Cohort Study. J Gen Intern Med 2020; Feb 10. doi: 10.1007/s11606-020-05653-0. [Epub ahead of print]
Implications for practice and research
Patients with hospital-onset sepsis are less likely to receive sepsis bundle adherent care compared with community-onset sepsis, reasons for which are multifactorial.
High-quality prospective cohort studies are needed to explore disparities in adherence, factors affecting non-adherence and its effect on mortality.
Adherence to sepsis bundles is associated with good outcomes in community-onset sepsis.1 Although evidence for similar benefit is lacking in hospital-onset sepsis, a uniform protocol such as SEP-1 (Severe Sepsis and Septic Shock Early Management Bundle-1) is recommended for all types of sepsis. Limited data suggest disparity in adherence to SEP-1 between community-onset sepsis and hospital-onset sepsis, with …
Competing interests None declared.
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Provenance and peer review Commissioned; internally peer reviewed.
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