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Commentary on: Li M, Li S, Chavarro JE, et al. Prepregnancy habitual intakes of total, supplemental, and food folate and risk of gestational diabetes mellitus: a prospective cohort study. Diabetes Care 2019;42:1034–41.
Implications for practice and research
Recent data show that gestational diabetes mellitus (GDM) prevalence has increased during the past 20 years.1 Pre-pregnancy supplementation with folic acid may be a simple, low-cost strategy to reduce maternal and infant morbidities associated with GDM.
Further studies are needed to identify the optimal dose of pre-pregnancy folic acid to reduce the incidence of GDM and to investigate long-term effects in offspring.
Context
Rates of GDM are rising worldwide and associated with adverse perinatal outcomes and long-term cardiometabolic risk in mothers and their offspring.1 This large prospective cohort study investigates the association between pre-pregnancy habitual folate intake and the risk GDM.2
Methods
The purpose of this study was to …
Footnotes
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Competing interests None declared.
Provenance and peer review Commissioned; internally peer reviewed.
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