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Child health
Moderate-to-vigorous exercise is beneficial and can improve symptoms of fatigue and depression in young people with paediatric-onset multiple sclerosis and other demyelinating conditions
  1. Karen McGuigan1,
  2. Charles J McGuigan2
  1. 1School of Nursing and Midwifery, Queen’s University Belfast, Belfast, UK
  2. 2Data and Analysis, NorthWest Research, NI, Londonderry, UK
  1. Correspondence to Dr Karen McGuigan, School of Nursing and Midwifery, Queen’s University Belfast, Belfast BT9 7BL, UK; k.mcguigan{at}qub.ac.uk

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Commentary on: Stephens S, Shams S, Lee J, et al. Benefits of physical activity for depression and fatigue in multiple sclerosis: a longitudinal analysis. J Pediatr 2019;209:226–32. https://doi.org/10.1016/j.jpeds.2019.01.040

Implications for practice and research

  • Young people with paediatric-onset multiple sclerosis (POMS) experience increased depression and fatigue across illness duration; healthcare professionals should be cognisant of the need to address these symptoms to ensure improved well-being and trajectory of these psychosocial aspects over time.

  • Additional longitudinal research among young people with MS is required to address symptomology and improve well-being among this grouping; and also to inform trends, potential interventions and treatment for the adult population.

Context

Paediatric-onset multiple sclerosis presents in childhood or adolescence with fatigue and depression common among those living with POMS.1 Fatigue and depression are often comorbid conditions that have been consistently …

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