Article Text

Download PDFPDF
Care of the older person
Should aspirin be used for primary prevention in the healthy elderly?
  1. David Thompson
  1. School of Nursing and Midwifery, Queen’s University Belfast, Belfast, UK
  1. Correspondence to Professor David Thompson, School of Nursing and Midwifery, Queen’s University Belfast, Belfast BT9 7BL, UK; David.Thompson{at}qub.ac.uk

Statistics from Altmetric.com

Commentary on: McNeil JJ, Wolfe R, Woods RL, et al. Effect of aspirin on cardiovascular events and bleeding in the healthy elderly. N Engl J Med 2018;379:1509–18.

Implications for practice and research

  • Low-dose aspirin as a primary prevention measure in older adults results in a significantly higher risk of major haemorrhage and does not result in a significantly lower risk of cardiovascular disease (CVD) than placebo.

  • All patients taking aspirin for primary prevention should be informed of the risk of major bleeding and the minimal benefits in terms of CVD events.

  • More research related to low-dose aspirin for primary prevention in younger age groups is warranted.

Context

Aspirin is a wonder drug—it is the most used drug worldwide and recently celebrated its 120th birthday—and has been regarded as a key …

View Full Text

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.