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Cohort study
Among infants at hereditary risk for type 1 diabetes, the introduction of solid foods before or after 4–5 months of age is associated with increased diabetes risk
  1. Lagerros Trolle Ylva
  1. Department of Medicine, Unit of Clinical Epidemiology, Karolinska Instituet, Stockholm, Sweden
  1. Correspondence to: Dr Lagerros Trolle Ylva, Department of Medicine, Unit of Clinical Epidemiology, Karolinska Institutet, T2, Stockholm SE 171 76, Sweden; ylva.trolle{at}

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Implications for practice and research

  • The safe age to introduce solid foods in children genetically susceptible for type 1 diabetes is between 4 and 5 months of age.

  • Continued breastfeeding during the introduction of solid foods may reduce the risk of type 1 diabetes.

  • Large prospective studies are still required to disentangle the associations between perinatal and infant food exposures and type 1diabetes.


While the increasing incidence of type 2 diabetes in children is receiving much attention, the predicted doubling of new type 1 diabetes cases younger than 5 years between 2005 and 2020 is also worrisome.1 Environmental factors, such as the timing of introducing solid foods to infants, have been on the agenda in the search for reasons for the rapid rise in type 1 …

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