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People with coexisting diabetes, chronic kidney disease and hypertension report the psychosocial effects of being prescribed multiple medications
  1. Alan J Zillich
  1. Department of Pharmacy Practice, Purdue University College of Pharmacy, Indianapolis, Indiana, USA
  1. Correspondence to: Dr Alan J Zillich, Department of Pharmacy Practice, Purdue Pharmacy Programs, Purdue University College of Pharmacy, 5th/3rd Bank Faculty Office Building, 640 Eskenazi Avenue, Indianapolis, IN 46202, USA; azillich{at}

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Implications for practice and research

  • Patients’ health and medication beliefs contribute to intentional medication non-adherence.

  • Interventions to improve intentional medication non-adherence must be patient-centred. Strategies such as team-based care and motivational interviewing should be considered.


Adherence to prescribed medication is estimated to occur in only 50% of patients. As the numbers of comorbid conditions and medications increase, the risk of medication non-adherence also increases. Interventions to improve medication adherence are often complex, multifactorial and individualised.1 Rooted in this individualised approach is a need to understand the behavioural motivations …

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