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Cohort study
At 15–20 weeks of pregnancy, various modifiable factors are associated with increased likelihood of a subsequent uncomplicated pregnancy
  1. Frederik J R Hermans1,
  2. Ewoud Schuit1,2
  1. 1Department of Obstetrics and Gynaecology, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands;
  2. 2Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht, The Netherlands
  1. Correspondence to : Frederik JR Hermans, Department of Obstetrics and Gynaecology, Academic Medical Centre, University of Amsterdam, Room H4-240, PO Box 22660, Amsterdam 1100 DD, The Netherlands; f.j.hermans{at}

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Commentary on: OpenUrlAbstract/FREE Full Text

Implications for practice and research

  • This study introduces the prediction of normal pregnancy outcomes, as opposed to the prediction of adverse pregnancy outcomes.

  • In view of the modifiable factors that are associated with increased chances of uncomplicated pregnancy, there is a need for intervention studies on the subject.


Traditional approaches in research and obstetric care focus on identifying risk indicators for adverse pregnancy outcomes rather than the prediction of uncomplicated pregnancy. A focus on identifying indicators of uncomplicated pregnancy may help women and their healthcare providers to select appropriate antenatal care, for example change in lifestyle factors or intensified monitoring, thus reducing the risk of …

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  • Competing interests None.