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  • Delivery of 100%, 40%, and blow-by humidity did not differ for change in croup scores in children with moderate croup

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Delivery of 100%, 40%, and blow-by humidity did not differ for change in croup scores in children with moderate croup

https://doi.org/10.1136/ebn.9.4.105

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    Scolnik D, Coates AL, Stephens D, et al. Controlled delivery of high vs low humidity vs mist therapy for croup in emergency departments: a randomized controlled trial. JAMA 2006;295:1274–80.OpenUrlCrossRefPubMedWeb of Science

    Q In children presenting to the emergency department (ED) with moderate croup, what is the relative effectiveness of 100% humidity with optimally sized water particles, 40% humidity, and humidity delivered by the blow-by technique?

    METHODS

    Embedded ImageDesign:

    randomised controlled trial (RCT).

    Embedded ImageAllocation:

    {concealed}.*

    Embedded ImageBlinding:

    blinded (healthcare providers, data collectors, and {data analysts}*).

    Embedded ImageFollow up period:

    30 and 60 minutes.

    Embedded ImageSetting:

    ED at the Hospital for Sick Children, Toronto, Ontario, Canada.

    Embedded ImagePatients:

    140 children 3 months to 10 years of age (mean age 25 mo, 69% boys) who presented with croup and had Westley croup scores ⩾2 out of 17 after a 30 minute rest period. Exclusion criteria were need for immediate nebulised epinephrine or intubation, potential alternative cause of stridor, history of chronic pulmonary disease other than asthma, coexistent systemic disease, previous …

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    Footnotes

    • ↵* Information provided by author.

    • For correspondence: Dr D Scolnik, Hospital for Sick Children, Toronto, Ontario, Canada. dennis.scolnik{at}sickkids.ca

    • Source of funding: Physicians’ Services Incorporated Foundation of Ontario.