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A telephone intervention reduced combined all cause mortality or admission for worsening heart failure in chronic heart failure

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Q In patients with chronic heart failure (HF), does a centralised telephone intervention by nurses reduce combined all cause mortality or admission for worsening HF?


Embedded ImageDesign:

randomised controlled trial (DIAL study).

Embedded ImageAllocation:


Embedded ImageBlinding:

blinded (outcome adjudicators).

Embedded ImageFollow up period:

mean 16 months.

Embedded ImageSetting:

51 centres (public and private hospitals and ambulatory settings) in Argentina.

Embedded ImagePatients:

1518 outpatients (mean age 65 y, 71% men) ⩾18 years of age, who had stable HF diagnosed ⩾3 months previously, no admissions in the past 2 months, and drug treatment that was not modified for ⩾2 months. Exclusion criteria included need for >1 medical visit per month; HF related to diseases other than ischaemic heart disease; reversible cardiomyopathy; recent myocardial infarction, unstable angina, cardiac …

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  • For correspondence: GESICA Investigators, c/o Dr H O Grancelli, Foundación GESICA, Buenos Aires, Argentina. gesica{at}

  • Source of funding: GESICA Foundation.