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Management of critically ill patients with a pulmonary artery catheter did not reduce all cause mortality

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Q In critically ill patients, does management with a pulmonary artery catheter (PAC) reduce hospital all cause mortality?


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randomised controlled trial (Pulmonary Artery Catheters in Management of patients in intensive care [PAC-Man] trial).

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Embedded ImageFollow up period:

until discharge from the acute hospital ward.

Embedded ImageSetting:

65 intensive care units (ICUs) in the UK.

Embedded ImagePatients:

1041 patients (mean age 65 y, 57% men) who were admitted to adult ICUs and identified by the treating clinicians as patients who should be managed with a PAC. Exclusion criteria included …

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  • For correspondence: Professor M Singer, University College London, London, UK. m.singer{at}

  • Source of funding: UK National Health Service Research and Development Health Technology Assessment Programme.