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Q What is the relative effectiveness of oral paracetamol (acetaminophen), oral non-steroidal anti-inflammatory drugs (NSAIDs), and combination treatment for acute pain relief after musculoskeletal injury?
randomised placebo controlled trial.
blinded (patients, healthcare providers, and outcome assessors).
Follow up period:
5–8 days after initial presentation. Pain was assessed up to 3 days.
emergency department (ED) of a university teaching hospital in Hong Kong.
300 patients ⩾16 years of age (mean age 37 y, 59% men) who presented to the ED with a painful acute limb injury. Exclusion criteria were substance abuse; dementia; indigestion; peptic ulceration or haemorrhage; recent anticoagulation; pregnancy; adverse reactions to study drugs; …
For correspondence: Dr T H Rainer, Accident and Emergency Medicine Academic Unit, Chinese University of Hong Kong, Shatin, Hong Kong.
Source of funding: no external funding.
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