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  • The WHO technique for intramuscular thigh vaccination in infants and toddlers had fewer adverse reactions than 2 other techniques

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The WHO technique for intramuscular thigh vaccination in infants and toddlers had fewer adverse reactions than 2 other techniques

https://doi.org/10.1136/ebn.9.1.9

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    Cook IF, Murtagh J. Optimal technique for intramuscular injection of infants and toddlers: a randomised trial. Med J Aust 2005;183:60–3.OpenUrlPubMedWeb of Science

    Q In infants and toddlers, which of 3 techniques for giving intramuscular thigh vaccinations results in the fewest adverse reactions?

    METHODS

    Embedded ImageDesign:

    randomised controlled trial.

    Embedded ImageAllocation:

    {concealed}.*

    Embedded ImageBlinding:

    blinded {participants and data collectors}.*

    Embedded ImageFollow up period:

    24 hours.

    Embedded ImageSetting:

    a general practice in Taree, New South Wales, Australia.

    Embedded ImageParticipants:

    375 consecutive healthy children who were 2, 4, 6, or 18 months of age.

    Embedded ImageIntervention:

    intramuscular injection into the anterolateral thigh of diphtheria-tetanus-acellular pertussis-hepatitis B vaccine (InfanrixHepB, GlaxoSmithKline) for children 2, 4, and 6 months of age or diphtheria-tetanus-acellular pertussis vaccine (Infanrix, GlaxoSmithKline) for children 18 months of age, using 1 of 3 techniques: Australian (23 gauge, 25 mm long needle inserted at the …

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    Footnotes

    • ↵* Information provided by author.

    • For correspondence: Dr I F Cook, Princess Park Clinic, Sheppaton, Victoria, Australia. drifcook{at}bigpond.com

    • Source of funding: Hunter Division of General Practice (for statistical analysis).