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  • An educational booklet did not improve adherence or symptoms in patients prescribed thyroxine for primary hypothyroidism

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An educational booklet did not improve adherence or symptoms in patients prescribed thyroxine for primary hypothyroidism

https://doi.org/10.1136/ebn.9.1.22

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    Crilly M, Esmail A. Randomised controlled trial of a hypothyroid educational booklet to improve thyroxine adherence. Br J Gen Pract 2005;55:362–8.OpenUrlAbstract/FREE Full Text

    Q Does an educational booklet addressing lay health beliefs about medicine-taking improve adherence in patients prescribed thyroxine for primary hypothyroidism?

    METHODS

    Embedded ImageDesign:

    randomised controlled trial.

    Embedded ImageAllocation:

    {not concealed}.*

    Embedded ImageBlinding:

    blinded (laboratory staff assessing thyroid stimulating hormone [TSH] assays).

    Embedded ImageFollow up period:

    median 96 days.

    Embedded ImageSetting:

    3 suburban general practices (18 physicians) in northwest England, UK.

    Embedded ImagePatients:

    332 patients ⩾18 years of age (mean age 62 y, 92% women) who were taking a stable dose of thyroxine (ie, dose unchanged over the previous 8 wks) for primary hypothyroidism caused by thyroidectomy, radio-iodine treatment, or autoimmune thyroiditis. Patients with serious illness were …

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    Footnotes

    • ↵* Information provided by author.

    Footnotes

    • ↵* Information provided by author.

    • For correspondence: Dr M Crilly, Department of Public Health, University of Aberdeen Medical School, Aberdeen, UK. mike.crilly{at}abdn.ac.uk

    • Source of funding: British Medical Association.