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Multisystemic therapy improved adherence to blood glucose testing in adolescents with type 1 diabetes

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Q Does multisystemic therapy increase adherence to blood glucose testing and insulin use, improve metabolic control, and reduce hospital use in adolescents with type 1 diabetes and chronically poor metabolic control?


Embedded ImageDesign:

randomised controlled trial.

Embedded ImageAllocation:


Embedded ImageBlinding:

blinded (assessor of reason for hospital visit, {data collectors, and data analysts}*).

Embedded ImageFollow up period:

7 months.

Embedded ImageSetting:

a diabetes clinic in a tertiary care children’s hospital in Detroit, Michigan, USA.

Embedded ImagePatients:

127 English speaking adolescents who were 10–17 years of age (mean age 13 y, 51% girls, 63% African-American) and had type 1 diabetes for ⩾1 year (mean 5 y), an average HbA1c concentration ⩾8% in the previous year, and a most recent HbA1c concentration ⩾8%. Adolescents with moderate to severe mental retardation or …

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  • * Information provided by author.

  • For correspondence: Dr D A Ellis, Department of Child Psychiatry and Psychology, Children’s Hospital of Michigan, Detroit, MI, USA. dellis{at}

  • Source of funding: National Institute of Diabetes and Digestive and Kidney Diseases.