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  • Timing and route of enteral tube feeding did not affect death or combined death or poor outcome in stroke and dysphagia

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Timing and route of enteral tube feeding did not affect death or combined death or poor outcome in stroke and dysphagia

https://doi.org/10.1136/ebn.8.4.117

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    Dennis MS, Lewis SC, Warlow C. Effect of timing and method of enteral tube feeding for dysphagic stroke patients (FOOD): a multicentre randomised controlled trial. Lancet 2005;365:764–72.OpenUrlCrossRefPubMedWeb of Science

    Q In patients with recent stroke and dysphagia, does early initiation of enteral tube feeding (ETF) (v no tube feeding for ⩾7 d) improve outcomes (study 1)? In these patients, does ETF by percutaneous endoscopic gastrostomy (PEG) (v nasogastric [NG] tube) improve outcomes (study 2)?

    METHODS

    Embedded ImageDesign:

    2 randomised controlled trials with similar designs (FOOD [Feed Or Ordinary Diet] trials).

    Embedded ImageAllocation:

    concealed.

    Embedded ImageBlinding:

    blinded {data collectors and outcome assessors}.*

    Embedded ImageFollow up period:

    6 months.

    Embedded ImageSetting:

    83 hospitals in 15 countries (study 1) and 47 hospitals in 11 countries (study 2).

    Embedded ImagePatients:

    patients who were admitted to hospital with recent stroke (⩽7 d before admission) and had dysphagia were enrolled in study 1 (n = 859, mean age 76 y, 46% men) if the …

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    Footnotes

    • ↵* Information provided by author.

    • A modified version of this abstract appears in ACP Journal Club.

    • For correspondence: Professor M Dennis, Western General Hospital, Edinburgh, UK. martin.dennised.ac.uk

    • Sources of funding: National Health Service Research and Development, UK; Stroke Association; Chief Scientist Office of the Scottish Executive; Chest, Heart, and Stroke, Scotland; Singapore Medical Research Council; and Royal Australasian College of Physicians.