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Review: subglottic secretion drainage reduces ventilator associated pneumonia

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Q Does subglottic secretion drainage (SSD) prevent ventilator associated pneumonia (VAP) in critically ill patients?


Embedded ImageData sources:

Medline, CINAHL, EMBASE/Excerpta Medica, Cochrane Library, Current Contents, and Biological Abstracts (1966 to May 2003); reference lists of retrieved studies and reviews; and authors of identified studies.

Embedded ImageStudy selection and assessment:

randomised controlled trials (RCTs) that compared SSD with no SSD in mechanically ventilated patients and reported pneumonia as an outcome. Methodological quality of individual studies was assessed based on allocation concealment and blinding.

Embedded ImageOutcomes:

VAP. Secondary outcomes were mortality, intensive care unit (ICU) length of stay (LOS), hospital LOS, ventilation duration, and time from intubation to diagnosis of pneumonia.


5 RCTs (n = 896) met the selection criteria. …

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  • For correspondence: Dr C Dezfulian, 10 Center Drive, Building 10, Room 7D43, Bethesda, MD, USA.

  • Sources of funding: Department of Veterans Affairs; Agency for Healthcare Research and Quality; and National Institutes of Health.