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Patient self management of anticoagulants resulted in fewer major complications than clinic-based management

https://doi.org/10.1136/ebn.8.3.87

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    Menéndez-Jándula B, Souto JC, Oliver A, et al. Comparing self-management of oral anticoagulant therapy with clinic management: a randomized trial. Ann Intern Med 2005;142:1–10.OpenUrlCrossRefPubMedWeb of Science

    Q Is patient self management of oral anticoagulants as efficacious and safe as management in an anticoagulation clinic?

    METHODS

    Embedded ImageDesign:

    randomised controlled trial (RCT).

    Embedded ImageAllocation:

    concealed.

    Embedded ImageBlinding:

    blinded (outcome assessors of complications).

    Embedded ImageFollow up period:

    median 11.8 months.

    Embedded ImageSetting:

    a university affiliated hospital in Barcelona, Spain.

    Embedded ImagePatients:

    737 ambulatory patients ⩾18 years of age who had received anticoagulant treatment for ⩾3 months.

    Embedded ImageIntervention:

    self management (n = 368) or clinic-based management (n = 369) of oral anticoagulant treatment with acenocoumarol. Self management training included a small group, education programme delivered by a specialist nurse in two 2-hour sessions. Content included use of a coagulometer, interpretation of international normalised ratios (INRs), and adjustment of doses. …

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    Footnotes

    • For correspondence: Dr J C Souto, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain. jsoutohsp.santpau.es

    • Source of funding: in part, Roche Diagnostic SL.