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Home based and hospital based IV antibiotics for cellulitis had similar effects on clinical outcomes

https://doi.org/10.1136/ebn.8.3.79

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    Corwin P, Toop L, McGeoch G, et al. Randomised controlled trial of intravenous antibiotic treatment for cellulitis at home compared with hospital. BMJ 2005;330:129.OpenUrlAbstract/FREE Full Text

    Q What is the relative efficacy of home based compared with hospital based intravenous (IV) antibiotics for treatment of cellulitis?

    METHODS

    Embedded ImageDesign:

    randomised controlled trial.

    Embedded ImageAllocation:

    concealed.

    Embedded ImageBlinding:

    unblinded.

    Embedded ImageFollow up period:

    ⩾4 weeks.

    Embedded ImageSetting:

    metropolitan Christchurch, New Zealand.

    Embedded ImagePatients:

    200 patients ⩾16 years of age, who presented to the emergency department (ED) with clinical signs of cellulitis and required IV antibiotics because of severity of cellulitis or failure of oral antibiotic treatment; were mentally competent; had a telephone at home and a caregiver nearby; and resided in metropolitan Christchurch. Exclusion criteria included pregnancy, IV treatment for cellulitis of the same site in the previous month, ⩾2 signs of systemic sepsis (temperature >38°C or <36°C, heart rate >90 beats/min, …

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    Footnotes

    • For correspondence: Dr P Corwin, Christchurch School of Medicine and Health Sciences, Christchurch, New Zealand. paul.corwinchmeds.ac.nz

    • Source of funding: no external funding.