Article Text

Download PDFPDF
Review: a low clinical probability plus a normal d-dimer test result excludes a diagnosis of deep venous thrombosis

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

OpenUrlAbstract/FREE Full Text

Q In patients with suspected deep venous thrombosis (DVT), is a combination of rapid d-dimer testing and estimation of clinical probability accurate for excluding a diagnosis of DVT?


Embedded ImageData sources:

Medline (1993–2003), Cochrane Database of Abstracts and Reviews, and bibliographies of relevant articles.

Embedded ImageStudy selection and assessment:

prospective studies (published in English) of consecutive outpatients with features of DVT that used a rapid d-dimer assay on at least a subgroup of patients; estimated the risk of DVT using a validated clinical probability tool that categorised patients as having low, intermediate, or high risk for DVT; evaluated outpatient data separately if inpatients were included; evaluated DVT data separately if patients with pulmonary embolism were included; had 100% patient follow up at ⩾3 months; …

View Full Text


  • For correspondence: Dr T L Fancher, Division of General Medicine, University of California at Davis, Sacramento, CA, USA.

  • Source of funding: US Health Resources and Services Administration’s Faculty Development in Primary Care.