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Review: magnesium prophylaxis after cardiac surgery reduces the risk of arrhythmia and atrial fibrillation

https://doi.org/10.1136/ebn.8.2.55

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    Shiga T, Wajima Z, Inoue T, et al. Magnesium prophylaxis for arrhythmias after cardiac surgery: a meta-analysis of randomized controlled trials. Am J Med 2004;117:325–33.OpenUrlCrossRefPubMedWeb of Science

    Q Does magnesium prophylaxis after cardiac surgery reduce the risk of arrhythmia?

    METHODS

    Embedded ImageData sources:

    Medline (1966 to June 2003), EMBASE/Excerpta Medica (1980 to June 2003), Cochrane Controlled Trials Register (Issue 3, 2003), and hand searches of references of reports and reviews.

    Embedded ImageStudy selection and assessment:

    randomised controlled trials (RCTs) in any language that compared a single, fixed dose of prophylactic magnesium (intravenous, central, or intracoronary administration) with control (placebo or routine care) after cardiac surgery. 2 independent reviewers assessed the methodological quality of individual trials using the 5 point Jadad scale.

    Embedded ImageOutcomes:

    atrial fibrillation (AF), supraventricular arrhythmia (SA) and ventricular arrhythmia (VA), serum magnesium concentration …

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    Footnotes

    • For correspondence: Dr T Shiga, Department of Anesthesia, Chiba Hokusoh Hospital, Nippon Medical School, Chiba, Japan. QZX02115nifty.ne.jp; Shigataol.com

    • Source of funding: no external funding