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Treatment
Review: a single dose of oral naproxen or naproxen sodium reduced acute postoperative pain in adults

https://doi.org/10.1136/ebn.8.2.53

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    Mason L, Edwards JE, Moore RA, et al. Single dose oral naproxen and naproxen sodium for acute postoperative pain. Cochrane Database Syst Rev 2004;(4):CD004234.

    Q Is a single dose of oral naproxen or naproxen sodium effective and safe for acute postoperative pain in adults?

    METHODS

    Embedded ImageData sources:

    Cochrane Library (Issue 4, 2002), Medline and PreMedline (1966–2002), PubMed (1966–2002), EMBASE/Excerpta Medica (1980–2002), Oxford Pain Relief Database (based on 40 hand searched journals from 1954–94), unpublished trials held in house, and reference lists of retrieved articles.

    Embedded ImageStudy selection and assessment:

    published and unpublished randomised, double blind, clinical trials in any language that compared a single oral dose of naproxen or naproxen sodium with placebo (⩾10 patients/group) in adults (⩾12 y) with moderate to severe pain after a surgical procedure in a day surgery or inpatient setting; pain intensity had …

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    Footnotes

    • For correspondence: Dr R A Moore, c/o Pain Research Unit, Churchill Hospital, Oxford, UK. andrew.moorepru.ox.ac.uk

    • Source of funding: Oxford Pain Relief Trust.