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Volunteers trained in CPR and use of automated external defibrillators increased survival after out of hospital cardiac arrest

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Q Do more patients with out of hospital cardiac arrest survive to hospital discharge when response teams of lay volunteers trained in cardiopulmonary resuscitation (CPR) also use automated external defibrillators (AEDs)?


Embedded ImageDesign:

cluster randomised controlled trial (Public Access Defibrillation [PAD] Trial).

Embedded ImageAllocation:

{not concealed}.*

Embedded ImageBlinding:

blinded (data collectors and outcome assessors).

Embedded ImageFollow up period:

to hospital discharge. Community units were involved for a mean 22 months.

Embedded ImageSetting:

993 community units in 24 North American regions.

Embedded ImagePatients:

patients ⩾8 years of age with out of hospital cardiac arrest.

Embedded ImageIntervention:

993 community facilities (eg, shopping malls, recreation centres, hotels, and apartment complexes) were eligible for randomisation as a community unit, either individually or as a group if they had a pool of lay volunteer responders able to deliver an AED within 3 minutes …

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  • * Information provided by author.

  • For correspondence: Dr A Hallstrom, Public Access Defibrillation Clinical Trial Center, University of Washington, Seattle, WA, USA.

  • Sources of funding: National Heart, Lung and Blood Institute; American Heart Association; Guidant Foundation; Medtronic. Devices supplied by Cardiac Science Survivalink; Medtronic Physio-Control; Philips Medical Systems Heartstream; Laerdal Medical.