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  • A multifaceted, home based, environmental intervention reduced asthma related morbidity in children with atopic asthma

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A multifaceted, home based, environmental intervention reduced asthma related morbidity in children with atopic asthma

https://doi.org/10.1136/ebn.8.2.43

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    Morgan WJ, Crain EF, Gruchalla RS, et al; for the Inner-City Asthma Study Group. Results of a home-based environmental intervention among urban children with asthma. N Engl J Med 2004 9;351:1068–80.OpenUrlCrossRefPubMedWeb of Science

    Q Is a multifaceted, home based, environmental intervention (HBEI) effective for improving asthma related outcomes in inner city children with atopic asthma?

    METHODS

    Embedded ImageDesign:

    randomised controlled trial.

    Embedded ImageAllocation:

    {concealed}.*

    Embedded ImageBlinding:

    blinded (outcome assessors).

    Embedded ImageFollow up period:

    1 year of intervention followed up by a 1 year observational period.

    Embedded ImageSetting:

    7 major cities in the US.

    Embedded ImagePatients:

    937 children 5–11 years of age (mean age 7.7 y, 63% boys) who had atopic asthma and resided in districts in which ⩾20% of households had incomes below the federal poverty level. Children were also required to have had ⩾1 asthma related hospital admission or 2 unscheduled asthma related visits to a clinic or emergency department during the previous 6 months and a positive skin test in response to ⩾1 of 11 indoor allergens.

    Embedded ImageIntervention:

    a 1 year …

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    Footnotes

    • ↵* Information provided by author.

    • For correspondence: Dr W J Morgan, Arizona Respiratory Center, University of Arizona, Tucson, AZ, USA. wmorganresp-sci.arizona.edu

    • Sources of funding: National Institute of Allergy and Infectious Disease; National Institute of Environmental Health Sciences; National Center for Research Resources.