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Prognosis
Having a stroke increased the risk of developing dementia in older people

https://doi.org/10.1136/ebn.8.1.25

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    Ivan CS, Seshadri S, Beiser A, et al. Dementia after stroke: the Framingham Study. Stroke 2004;35:1264–8.OpenUrlAbstract/FREE Full Text

    Q In older people, does having a stroke increase the risk of developing dementia?

    METHODS

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    nested case-control study of patients who had a stroke and 5 randomly allocated age and sex matched controls followed up for ⩽10 years. Patients and controls were identified from a stroke free and dementia free inception cohort drawn from the Framingham Study and regularly examined over a 20 year period (1982–2002).

    Embedded ImageSetting:

    town of Framingham in Massachusetts, USA.

    Embedded ImagePatients:

    212 patients (mean age 79 y, 61% women) who had their first stroke at <95 years of age, were free from dementia at the time, survived the stroke, and were available for evaluation 6 months after the index stroke. The controls were required to be alive, free from stroke and dementia, …

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    Footnotes

    • For correspondence: Dr P A Wolf, Boston University School of Medicine, Boston, MA, USA. pawolfbu.edu

    • Sources of funding: National Institutes of Health; National Institute of Ageing; National Institute of Neurological Disorders and Stroke; and Boston University Alzheimer’s Disease Center.