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Review: all forms of nicotine replacement therapy are effective for smoking cessation

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Q What is the effectiveness of different preparations of nicotine replacement therapy (NRT) in achieving long term smoking cessation?


Embedded ImageData sources:

Cochrane Tobacco Addiction Group Specialized Trial Register, which is based on searches of the Cochrane Central Register of Controlled Trials (Issue 4, 2003), Medline, EMBASE/Excerpta Medica, PsycLIT/PsycINFO, and Science Citation Index.

Embedded ImageStudy selection and assessment:

randomised controlled trials (RCTs) ⩾6 months in duration that compared NRT (including gum, transdermal patch, intranasal spray, and inhaled and oral preparations) with placebo or no treatment, or compared different doses of NRT, and assessed smoking cessation. Methodological quality of individual trials was assessed for …

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  • For correspondence: Mrs L Stead, Department of Primary Health Care, Institute of Health Sciences, Oxford, UK.

  • Sources of funding: NHS Research and Development National Cancer Programme, UK and NHS Anglia and Oxford Region Research and Development Programme, UK.