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Cardiac rehabilitation improved exercise tolerance after a myocardial infarction in older patients

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Q In patients >45 years of age who have had a myocardial infarction (MI), does cardiac rehabilitation (CR) improve short and long term exercise tolerance?


Embedded ImageDesign:

randomised controlled trial.

Embedded ImageAllocation:


Embedded ImageBlinding:

blinded (healthcare providers, data collectors, and outcomes assessors).

Embedded ImageFollow up period:

14 months.

Embedded ImageSetting:

a university CR unit in Florence, Italy.

Embedded ImagePatients:

270 patients >45 years of age (age range 46–86 y, 68% men) who were referred to the CR unit for functional evaluation 4–6 weeks after MI. Exclusion criteria included severe cognitive impairment or physical disability, left ventricular ejection fraction <35%, contraindications to vigorous physical exercise, and living too far from the CR unit.

Embedded ImageInterventions:

Patients were allocated in an age (3 age groups predefined as middle aged 45–65 …

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  • For correspondence: Dr N Marchionni, Department of Critical Care Medicine and Surgery, University of Florence and Azienda Ospedaliera Careggi, Florence, Italy.

  • Sources of funding: National Research Council and the Regional Government of Tuscany, Italy.