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QUESTION: In patients with type 2 diabetes mellitus, what are the optimal blood pressure (BP) goals and pharmaceutical agents to reduce risk of complications?
Data sources
The Cochrane Collaboration Diabetes Group report was used to identify studies published before 1997. Recent studies were identified by searching Medline in May 2000 and again in April 2002. Bibliographies of meta-analyses and review articles were scrutinised, and experts in the field were contacted for further studies.
Study selection
Studies were selected if they were randomised controlled trials (RCTs) that compared an antihypertensive drug with placebo, the effects of different target BP levels, or the effects …
Footnotes
Source of funding: American College of Physicians.
For correspondence: Dr S Vijan, Veterans Affairs Health Services Research, Development Center for Practice Management and Outcomes Research, Ann Arbor, MI, USA. svijan{at}umich.edu